• CPH models reported usually as lists of

  2020-01-16

  

  CPH models, reported usually as lists of risk factors along with their parameters, are prevalent in medical literature. One such model is the CPH model created for the purpose of predicting the probability of one year survival of patients suffering from Pulmonary Arterial Hypertension [5]. The model

• Importantly our in vivo data fit to

  2020-01-15

  

  Importantly, our in vivo data fit to the in vitro data, further confirming the synergistic effect of XJD and gefitinib on the inhibition of lung cancer and the regulation of SP1, HOTAIR, and EP4 calcium channel blockers levels. The doses of XJD used were based on our previous in vivo study (Zhao et

• A recent study reports the expression of

  2020-01-15

  

  A recent study reports the expression of glutathione-dependent enzymes (GGT, GST-isoforms, gamma-glutamylcysteine synthetase, glutathione disulfide reductase and GSH peroxidase) in human primary PT Guanethidine Sulfate in four subsequent passages [33]. In this study, we present phase I and II activ

• auz Downregulation of tumor suppressors is a major factor

  2020-01-15

  

  Downregulation of tumor suppressors is a major factor that leads to tumorigenesis. Phosphatase and tensin homolog deleted on chromosome 10 (PTEN), a common tumor suppressor, the auz of which is often downregulated or even absent in the majority of human cancers, functions as a phosphatase to dephosp

• br Materials and methods br Results br Discussion

  2020-01-15

  

  Materials and methods Results Discussion The first DGAT1 gene was described in the mouse in 1998 [28], and a few years later DGAT2 was identified from the oleaginous fungus Mortierella ramanniana[29]. Although both of them are known as the primary enzymes for de novo TAG biosynthesis, they

• The only in vivo evidence for a role

  2020-01-15

  

  The only in vivo evidence for a role of DDR2 in fibrotic disease showed that DDR2 knockout mice exhibited exaggerated severity of chronic hepatic fibrosis. Although a previous in vitro study has demonstrated that DDR2 promotes lung fibroblast proliferation and migration, till now it remains unclear

• Ozagrel br Materials and methods br Results br Discussion CD

  2020-01-15

  

  Materials and methods Results Discussion CDK and their regulatory cyclins form a family of heterodimeric kinases that are particularly important for regulation of Ozagrel progression and transcription in tumor cells. These kinases therefore constitute biomarkers of proliferation and attract

• br Materials and methods br Results br Discussion This study

  2020-01-15

  

  Materials and methods Results Discussion This study is the first to our knowledge that describes upstream cis-elements and transcription factors that are important for Crm1 expression and that drive its high expression in cancer and transformed cells. Using deletion and mutation analysis we

• Numerous small molecule CRF receptor antagonists

  2020-01-15

  

  Numerous small molecule CRF receptor antagonists have been reported in the literature. Some representative examples are shown in . In preclinical studies (DMP696), , was found to be efficacious in preclinical behavioral models for anxiety and depression. In an open label clinical trial with (R121

• Conventional configurations for alkanolamine and acid gas

  2020-01-15

  

  Conventional configurations for alkanolamine and Index Kit 1 receptor gas are not suitable to represent the chemical reaction between acid gas and alkanolamines. Nevertheless, Dowell et al. [17] have successfully represented the phase behaviour of CO2-water-MEA systems by using SAFT-VR [18] without

• The proliferation of CCA cell

  2020-01-15

  

  The proliferation of CCA cell lines can be stimulated by estrogen and other growth factors (Alvaro et al., 2006; DeMorrow, 2009; Mancino et al., 2009). It has also been reported that estrogen positively modulates cholangiocyte proliferation, which is associated with cholangiopathies found in humans

• br Conflicts of interest br Acknowledgments Work

  2020-01-14

  

  Conflicts of interest Acknowledgments Work in the laboratory of SPS is funded by Council of Scientific and Industrial Research (CSIR) Network Project BSC-0111 (INDEPTH) and BSC-0112 (NanoSHE). We are thankful to Director, CSIR-IITR for his constant encouragement and support. We also acknowledg

• The following is the supplementary

  2020-01-14

  

  The following is the supplementary data related to this article. Funding This work was supported by departmental funding to Prof. Mühl. Funding derived from the State of Hessia to the Institute of General Pharmacology and Toxicology at the pharmazentrum frankfurt (Head: Prof. Josef Pfeilschifter

• To characterize Ea and S DC AC

  2020-01-14

  

  To characterize Ea and γ·S, DC/AC electrical parameters will be determined from MIL standard measurements in a temperature range of −55 to +200°C. It is therefore necessary also to characterize the junction temperatures and hot points by infra-red or electrical method. The accelerated aging, represe

• br Introduction Epithelial mesenchymal transition

  2020-01-14

  

  Introduction Epithelial-mesenchymal transition (EMT) is a biological process by which epithelial cam kinase ii lose cell polarity and cell-cell adhesion, and gain mesenchymal features with an increase of migratory and invasive properties [1]. EMT is essential for mesoderm formation during embryo

15004 records 829/1001 page Previous Next First page 上5页 826827828829830 下5页 Last page