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phosphodiesterase inhibitors br Discussion Treatment of pati
2019-05-31
Discussion Treatment of patients with vaginal leiomyosarcoma is challenging because of the rarity of this disease and a lack of controlled clinical trials comparing management strategies. At this time primary surgery remains the mainstay of management of vaginal leiomyosarcoma. Treatment plans sh
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br Introduction Once metastatic breast cancer
2019-05-31
Introduction Once metastatic breast cancer lipoxygenase are in the bone marrow, they hijack signals coming from the normal bone remodelling process and promote bone degradation [1]. Bone degradation is caused by osteoclasts, which have the unique property to dissolve bone mineral and degrade the
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At autopsy approximately cm of blood and clots were
2019-05-31
At autopsy, approximately 180cm3 of blood and clots were found inside the pericardial cavity. Careful inspection of the SAG supplier Supplier showed a deep lesion, 2mm in length, on the antero-lateral aspect of the vessel (Fig. 1) 2cm above the valvular plane (Fig. 2). On the medial aspect of the ri
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Several mechanisms have been proposed Due
2019-05-30
Several mechanisms have been proposed. Due to a greater birth interval, children who are breastfed will enjoy a greater period of exclusive parental attention as either the only child or youngest child. This exclusivity might have an effect on intelligence. It has been consistently observed that the
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Estes n meros d o um ind cio
2019-05-30
Estes números dão um indício do clima de insegurança, e muitas vezes de terror, que pairou sobre o país no período. Este ambiente foi explorado em diversos sentidos pelo regime fujimorista. De um lado, atribuiu para si o mérito de ter desarticulado ensational new insurgência e pacificado o país, o q
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In a previous report it was speculated that withdrawal syndr
2019-05-30
In a previous report, it was speculated that withdrawal syndrome after IM cessation was related to a loss of blocking tyrosine kinases, such as c-kit and platelet-derived growth factor receptor (PDGFR) [2]. The inhibition of c-kit and PDGFR by IM reduces and increases the number of osteoclasts and o
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In the days before Christmas adverse weather conditions and
2019-05-30
In the days before Christmas, 1952, adverse weather conditions and the burning of sulphurous coal led to the death of almost 12 000 people in London. Despite improvements in pollution prevention since the “Great Smog”, London continues to experience toxic air pollution linked to thousands of prematu
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Predicting the potential effects of climate
2019-05-30
Predicting the potential effects of climate change on the incidence and distribution of infectious gastroenteritis can assist public health providers to control and prevent severe outbreaks in the future. Implementation of programmes for rotavirus vaccination clearly shows benefit and should be an K
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order naloxone hydrochloride Perhaps counter intuitively the
2019-05-30
Perhaps counter-intuitively, the most strategic tobacco control policies to reduce adolescent smoking and secondhand smoke exposure in LMICs may not be those targeting adolescents. Targeted campaigns can be expensive, and are unlikely to be as effective as the more affordable tobacco control policie
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In our study ES SCLC
2019-05-30
In our study, ES-SCLC patients in the CIT group were on average older than those in the control group. However, the multivariate analysis showed that age had no effect on the prognosis of these patients. Therefore, age was no a confounding factor, although it has been reported that effector cell fun
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GSK2656157 br Material and methods br Results br
2019-05-30
Material and methods Results Discussion The present study provides clinical, molecular, and in vitro electro-physiological evidence that a rare SNP (KCNE1-D85N) can act as a genetic modifier in LQTS. In general, SNPs are thought to be non-pathological, but some have been reported to modify
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The results described thus far suggest
2019-05-30
The results described thus far suggest that PtAF-induced atrial remodeling combined with acute atrial stretch facilitates anchoring of 3-D scroll waves to the border of atrial pectinate muscle and prolongs their life span in favor of AF maintenance. However, why is it that scroll waves anchor to the
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br What is the best pacing
2019-05-30
What is the best pacing algorithm for vasovagal syncope? Conclusions Conflict of interest Introduction The number of implantations of cardiovascular implantable electronic devices (CIEDs), including permanent pacemakers (PPMs), implantable cardioverter defibrillators (ICDs), and cardiac
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br Growth supportive characteristics of the BM vascular nich
2019-05-30
Growth-supportive characteristics of the BM vascular niche Similar to normal tissues, tumours also need functional blood vessels to support their growth via the delivery of oxygen and nutrients. When a DTC starts proliferating into a micrometastasis, it drives angiogenesis to build new blood vess
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br Results There were cases where
2019-05-30
Results There were 232 cases where cryotherapy was used in 214 patients between 1994 and 2015. There were 96 male and 118 female. The age of patients ranged from 4 to 95. All patients had undergone imaging studies for evaluation. A majority of cases consisted of active or aggressive benign tumors
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