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br Experimental Procedures br Author Contributions br
2018-11-02
Experimental Procedures Author Contributions Acknowledgments We thank Keisuke Okita and Shinya Yamanaka for providing the hiPSC lines 409B2 and 604B1, Knut Woltjen for providing PB-MCSII, Akitsu Hotta for providing the PBase II vector and instructions for transducing the piggyBac vectors, a
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Conversely not much is known about the origin
2018-11-02
Conversely, not much is known about the origin of these mutations. Their high frequency, combined with the proficient DNA repair of hESC (Sokolov and Neumann, 2013), suggests that these selective undergo profuse DNA damage in culture. Studies on genetic mosaicism in hESC cultures, which reflect the
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hepititis b Accumulating evidence indicates that treatment u
2018-11-02
Accumulating evidence indicates that treatment using extracellular vesicles (EVs) have multiple advantages over cell therapy, because EVs are stable in the circulation without losing function and exhibit a superior safety profile (Vader et al., 2016). In particular, MSCs are an attractive source of
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Scale similarity criteria the Rayleigh number and the
2018-11-02
Scale similarity criteria (the Rayleigh number and the rotation parameter, constructed from the scale quantities) specified in the course of the simulations, were determined for the conjugate and the non-conjugate settings as follows: where ΔT0 is the temperature difference (ΔT0=–). In the conjuga
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Narcolepsy may be mono symptomatic
2018-11-02
Narcolepsy may be mono-symptomatic (only ES) or oligo-symptomatic (ES and cataplexy). The degree of ES is variable and the attacks of cataplexy might involve several muscle groups being triggered by emotions [1,3]. The use of modafinil in the treatment of narcolepsy is a first option for the treatm
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Para Keynes que construye su m todo como un sistema
2018-11-01
Para Keynes, que construye su método como un sistema económico de tres variables independientes (la propensión marginal CGP-41251 consumir, la eficacia marginal del capital y la tasa de interés) que determinan a dos dependientes (el nivel de ingreso y el volumen de ocupación), la verdadera determina
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In order to further assess the
2018-11-01
In order to further assess the specificity of the 4-biomarker panel in detecting lung cancer patients, we collected a group of patients with benign lung diseases, including granuloma, pulmonary inflammatory pseudotumor, tuberculosis, pulmonary nodule and sequestration. Of note, these patients were d
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Thirty seven studies reported ReA following Campylobacter n
2018-11-01
Thirty-seven studies reported ReA following Campylobacter (n=19) and NTS infections (n=26) (Buxton et al., 2002, Bremell et al., 1991, Dworkin et al., 2001, Eastmond, 1983, Ekman et al., 2000, Gumpel et al., 1981, Hakansson et al., 1976, Hannu et al., 2002a, 2002b, Helms et al., 2006, Pitkanen et al
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Tumor relapse after radiotherapy is a
2018-11-01
Tumor relapse after radiotherapy is a significant challenge to oncologists. Tumor recurrence was generally due to radiation resistance, which was determined by both the intrinsic characteristics and the extrinsic microenvironment of cancer vorapaxar (Frank et al., 2010). The unique stem cell proper
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Findings from the most recent Global Burden
2018-11-01
Findings from the most recent Global Burden of Disease study, published in October 2016 in , show that in 2015, the mean life expectancy worldwide had reached roughly 72years. This is an increase of 10years since 2000, largely attributed to improvements in childbirth-associated and infant mortality,
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The mass spectrometry proteomic data have
2018-11-01
The mass spectrometry proteomic data have been deposited into the ProteomeXchange Consortium [2] via the PRIDE partner repository with the dataset identifier PXD001450. Data set analysis of avian eggshell matrix proteins A total of 261 proteins were identified using nr NCBI database. Keratins an
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br Data Fasting during the
2018-11-01
Data Fasting during the light phase reduced oxygen consumption in female mice fed either a high-fat or standard diet (SD) for 3 days (Fig. 1B), but during the dark phase, fasting only reduced oxygen consumption when mice were fed a background high-fat diet (Fig. 1A). In both the dark and light ph
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The present study tested whether children with
2018-11-01
The present study tested whether children with recent-onset tics are capable of suppressing their tics and if so, whether an environmental contingency (namely, reward) modifies this ability. Given evidence that reward can enhance inhibitory control in children without tics (Padmanabhan et al., 2011;
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The results of the present study
2018-11-01
The results of the present study should be interpreted with caution as there are several potential limitations. One possible explanation for our observed effects is that the adults responded at such lower levels than the adolescents, that it is harder to detect a reduction in responding after contin
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Unlike previous cross sectional studies we
2018-11-01
Unlike previous cross-sectional studies, we did not find DTI differences between CUs and non-using controls in white Phos-tag Acrylamide tracts associated with core limbic structures such as the hippocampus (e.g., fimbria; Zalesky et al., 2012; Yücel et al., 2010) and amygdala (e.g., uncinate fascic
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