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br Materials and Methods br Results br Discussion
2018-10-22
Materials and Methods Results Discussion Liver participates in a variety of enzymatic metabolic activities. Administration of ethanol causes elevation of serum ASP, ALT, ALP and total bilirubin levels in rats, indicating that ethanol may induce hepatocellular damages which in turn alters th
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The mechanism s of this taurine requirement for brain develo
2018-10-22
The mechanism(s) of this taurine requirement for lactacystin development are poorly understood. The influence of taurine may be exerted on cell division, migration or/and differentiation. These possibilities can be examined in a preparation of neural precursor cells (NPCs) collectively including ne
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conotoxin The presence of multi lineage mesenchymal stem cel
2018-10-22
The presence of multi-lineage mesenchymal stem conotoxin in the placenta has tremendous implications. Along with the multi-differentiation capability, the easy accessibility, the abundant source and no ethical concerns, placenta-derived MSCs (PMSCs) may be an attractive, alternative progenitor or st
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Potential candidates contributing to the fate determination
2018-10-22
Potential candidates contributing to the fate determination in the injured spinal cord include bone morphogenetic proteins (BMPs) — in particular BMP2 and BMP4, which strongly promote astroglial differentiation at the expense of oligodendroglial and neuronal differentiation (Bonaguidi et al., 2005;
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Using our screening we were able to
2018-10-22
Using our screening, we were able to confirm the previously determined cytogenetic karyotypes of 34 mESC lines and to further validate our method using 19 additional mESC lines with unknown cytogenetic karyotypes. Our study includes the screening of five mESC lines that produced germline transmissio
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Electric fields EFs provide a powerful
2018-10-22
Electric fields (EFs) provide a powerful signal with which to stimulate and guide migration of many types of cells in vitro, including NSCs (Cao et al., 2013; Feng et al., 2012a; Li et al., 2008; Meng et al., 2011; Yao et al., 2008, 2009; Zhao et al., 2006). Normally, weak EFs in the TCEP may aid i
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In order to enhance osteochondral commitment
2018-10-22
In order to enhance osteochondral commitment, we performed chondrogenic pre-induction of ATSC/β-TCP constructs. Ectopic bone formation was installed in more than 75% of samples, suggesting that a sufficient degree of determination was reached to obtain about as much new bone as with non-induced BMSC
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br Introduction Currently heart disease
2018-10-20
Introduction Currently, heart disease is the leading cause of mortality in the industrialized world, partly due to the inability of the heart to regenerate in adults; and also the dietary and life style changes leading to a marked increase in the incidence of type II diabetes (for review, see Arm
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The following are the supplementary data related to
2018-10-20
The following are the supplementary data related to this article. Conflict-of-interest disclosure Acknowledgments The authors would like to thank Ms. Kathleen Makielski for proofreading the manuscript. This work was supported by National Natural Science Foundation of China (grant number 81372
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ibmx br Materials and methods br Results br Discussion
2018-10-20
Materials and methods Results Discussion Conclusion Author contributions Acknowledgments This study was supported by a grant from the Innovative Research Institute for Cell Therapy (A062260) and supported by the a grant of the Korea Health Technology R&D Project through the Korea H
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I-BET-762 cost There was a decrease of NF B nuclear transloc
2018-10-20
There was a decrease of NF-κB nuclear translocation on immunofluorescence of lung tissue at 4h, in hMSC treated pigs versus untreated controls. The number of I-BET-762 cost with positively staining nuclei for NF-κB was significantly lower in the treatment group compared to controls. This suggests th
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solution dilution calculator br Author disclosure statement
2018-10-20
Author disclosure statement Acknowledgements Authors would like to thank Dr. T. Ramakrishna Murti for his valuable comments and linguistic corrections in the manuscript. Authors would also like to thank D.I Biotech (Seoul, Korea) for support to analyze neurite outgrowth. This work was supporte
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The host immune response has
2018-10-20
The host immune response has been identified as a critical regulator of tumor development and progression (Dunn et al., 2004; Fridman et al., 2013; Hadrup et al., 2013). Several types of immune MM-102 participate in immunosurveillance by direct killing or production of cytokines. Our expression pro
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Although the central nervous system is relatively immunotole
2018-10-20
Although the central nervous system is relatively immunotolerant (Barker and Billingham, 1977) and human fetus-derived NS/PCs and hESC-derived NS/PCs (hESC-NS/PCs) showed weak immunogenicity (Odeberg et al., 2005; Åkesson et al., 2009; Liu et al., 2013a), no studies to date have investigated the ext
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Further support for the hierarchical two
2018-10-20
Further support for the hierarchical two-stem-cell model came with the discovery of an additional reserve ISC marker locus, Hopx, encoding an atypical homeodomain protein with functions in early heart development (Chen et al., 2002). An IRES-CreERT2 cassette inserted into the endogenous Hopx locus r
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