• Introduction Atrial fibrillation AF is

  2019-06-27

  

  Introduction Atrial fibrillation (AF) is the most common arrhythmia in adults and the most common cause of embolic stroke. AF affects approximately 0.8 million patients in Japan alone, and its incidence is expected to grow exponentially [1–3]. However, the electrophysiological mechanisms of the ini

• notch signaling Introduction Personalized medicine is the ma

  2019-06-27

  

  Introduction Personalized medicine is the major goal of translational research in the post-genomic era. Numerous biomarkers have been identified by genomic or proteomic approach that can reclassify the disease notch signaling and predict clinical outcome. However, to define a specific disease pheno

• In this section we will try and address many of

  2019-06-27

  

  In this section we will try and address many of the frequently asked questions around preventive and prophylactic measures for patients either starting or already established on bone-targeted therapy (Figs. 2 and 3). In view of the difficulties in treating ONJ, preventive strategies would seem to ma

• br En general los resultados electorales

  2019-06-27

  

  En general, los resultados electorales de 2011 demuestran la identificación y cercanía lograda entre los movimientos sociales y Ollanta Humala, por lo menos en términos de adhesión electoral, la misma que se mantuvo en el tiempo pues en 2006 también estos sectores le otorgaron su voto. Así, la ele

• br Materials and methods br

  2019-06-27

  

  Materials and methods Results Discussion Although EMT can be induced by different factors under exogenous stimuli, it is intriguing to consider whether these EMT inducers are redundant because of their mechanistic similarity in EMT induction. The interplay and underlying mechanism between E

• Introduction Ewing s sarcoma ES is a

  2019-06-27

  

  Introduction Ewing\'s sarcoma (ES) is a high-grade neoplasm representing the second most common primary bone malignancy in both children and adults. With a peak incidence at 15 years, this disease accounts for 2% of childhood cancers [1–3]. ES is defined as a bone tumor which may occur at any site

• br Material and methods br Results br

  2019-06-27

  

  Material and methods Results Discussion Previously, various small studies reported that CRT is an effective therapy in patients with NAHF [7,10–15]. These studies demonstrated favorable outcomes in patients treated with CRT, including the ability to wean patients from intravenous inotropes

• Several mechanisms have been proposed Due to a greater birth

  2019-06-27

  

  Several mechanisms have been proposed. Due to a greater birth interval, children who are breastfed will enjoy a greater period of exclusive parental attention as either the only child or youngest child. This exclusivity might have an effect on intelligence. It has been consistently observed that the

• Por otra parte en su definici n experiencial y

  2019-06-27

  

  Por otra parte, en su definición experiencial y corporal, estas escenas colocan la Historia verdadera en otra dimensión, el relato de viaje. En efecto, lo que caracterizaría buena parte de esta crónica así como las dos primeras cartas cortesianas (al menos) es el relato del viaje de conquista, el én

• br Planteamientos Previos El presente estudio muestra la est

  2019-06-27

  

  Planteamientos Previos El presente estudio muestra la estrecha relación entre los procesos identitarios y las transformaciones de los contextos migratorios. Centrándose en el caso de los migrantes indígenas de Otavalo (Ecuador) en una de las ciudades del sur de España, la investigación parte de u

• br Materials and methods Eculizumab levels were measured

  2019-06-27

  

  Materials and methods Eculizumab levels were measured at Cambridge Biomedical using a manual ELISA method in which the microtitre plates are coated with C5, then blocked. Standards, controls, and unknowns were added. After incubation and washing, mouse anti-human IgG4 horseradish peroxidase (HRP)

• br Discussion Case reports of successful

  2019-06-27

  

  Discussion Case reports of successful chemotherapy desensitizations have been described for platinum agents, taxanes, anthracyclines, rituximab [8], and cytarabine [9], but not specifically clofarabine. For older patients with relapsed AML that are not candidates to receive anthracycline therapy,

• The Mexico City Policy is

  2019-06-27

  

  The Mexico City Policy is also flawed on evidentiary and public health grounds. A 2011 study found that enforcement of the Mexico City Policy by the George W Bush administration led to an increase in abortion rates in sub-Saharan Africa, probably because of decreased contraception access and increas

• CHIR-090 Cardiac troponin I cTnI is a well established sensi

  2019-06-26

  

  Cardiac troponin I (cTnI) is a well-established, sensitive, and specific marker of myocardial injury. However, evidence indicates that unrecognized myocardial injury may be occurring with certain conditions such as sepsis without acute coronary ischemic event, which demonstrate elevated cTnI levels.

• br Safety of continuation of warfarin

  2019-06-26

  

  Safety of continuation of warfarin during the perioperative period of pacemaker and defibrillator surgery An increasing body of literature has suggested that pacemaker and defibrillator INCB3344 weight without cessation of oral anticoagulation is safe and feasible. Goldstein et al. were among th

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