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Rs is a C T single nucleotide variation on
2018-11-15
Rs1524107 is a C/T single-nucleotide variation on human chromosome 7. It is single nucleotide polymorphisms in interleukin-6 (IL-6) gene. IL-6 are secreted by Toll-like receptor 2-expressing cells in response to the presence of Mycobacterium tuberculosis early in infection and are involved in anti-t
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Recently as reported by Xu G et al sorafenib
2018-11-15
Recently, as reported by Xu G et al., sorafenib in combination with low-dose homoharringtonine as a salvage therapy was successfully administrated and obtained CR in primary refractory FLT3-ITD mutant AML. In conclusion, regimen including HHT has been used as an alternative valid front line chemothe
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br Space syntax method for
2018-11-14
Space syntax method for interpreting mosque layouts The space syntax method is an approach developed to analyze spatial configuration. Space syntax aims to describe spatial models (e.g., mosque layouts) and represent these models in numerical and graphical forms, thus facilitating scientific inte
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dcb cost br New urbanization an inevitable
2018-11-14
New urbanization: an inevitable stage in the development of Chinese urbanization Between 1949 and 1978, urbanization in China witnessed as low growth in the early stage and drastic fluctuations in the late stage. Urbanization during this dcb cost was poorly developed, the urbanization level rema
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This study specifically aimed to achieve
2018-11-14
This study specifically aimed to achieve the following objectives: In previous studies, geometry is applied to experiments involving rats to determine the effect of geometry on wayfinding (Yaski and Eilam, 2007; Yaski et al., 2011a, 2012). In our study, geometry was defined in terms of its effect o
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ll-37 The light microscopic findings of leiomyosarcoma show
2018-11-14
The light microscopic findings of leiomyosarcoma show the typical morphology of smooth muscle tumors: alternating fascicles of spindle ll-37 with blunt-ended nuclei and eosinophilic cytoplasm (Fig. 4). However, renal leiomyosarcoma may also be confused with sarcomatoid renal cell carcinoma on histo
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br Results br Discussion Drug therapy for the H I
2018-11-14
Results Discussion Drug therapy for the H/I-injured inhibitor of catalase has focused largely on anti-oxidants (allopurinol, N-acetylcysteine), anti-excitotoxic agents (topiramate, memantine), and anti-inflammatory agents (cromolyn) (Juul and Ferriero, 2014; Hagberg et al., 2015). These therap
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Whatever the exact mechanism it
2018-11-14
Whatever the exact mechanism, it is clear that Wnt signaling levels need to be strictly controlled. It is well possible that somewhat higher Wnt levels, which are detrimental to stemness, can be tolerated if HSC survival is enhanced, which then would lead to better self-renewal at this somewhat high
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br Introduction The pattern of maternal
2018-11-14
Introduction The pattern of maternal alcohol consumption over the reproductive life course is greatly understudied. Research involving women׳s use of alcohol has tended to focus on short periods of their lives, generally during pregnancy (Anderson et al., 2013; Maloney et al., 2011; Liu, Mumford
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GSK461364 Recent progress in the field of matrix assisted la
2018-11-14
Recent progress in the field of matrix-assisted laser desorption/ionization mass spectrometry imaging (MALDI-MSI) has shed light on understanding the distribution of analytes in various tissues. MALDI-MSI is a powerful tool that can determine the distribution of hundreds of ionized analytes based on
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br Materials and Methods br
2018-11-14
Materials and Methods Results Discussion The homolog of the human tumor suppressor SCRIB was first characterized in Drosophila (Bilder et al., 2000). The product of human SCRIB, Scribble, is a multidomain protein acting as scaffold involved in multiple signaling pathways. Scribble is deregu
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Asiaticoside br Methods br Funding br Ethical clearance br R
2018-11-14
Methods Funding Ethical clearance Results We included 89 children as described in Fig. 2, with 281 PBs, comprising 189 pairs of successive PBs (average of 3.15 biopsies per patient). Characterization features are summarized in Table 2 and details provided in Supplementary Tables 1 and 2.
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In order to further assess the specificity of the biomarker
2018-11-14
In order to further assess the specificity of the 4-biomarker panel in detecting lung cancer patients, we collected a group of patients with benign lung diseases, including granuloma, pulmonary inflammatory pseudotumor, tuberculosis, pulmonary nodule and sequestration. Of note, these patients were d
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The results of the hierarchical regression suggest that coun
2018-11-14
The results of the hierarchical regression suggest that countries with higher mean years of schooling are less likely to report positive vaccine sentiment, however within a country those with some education hold more positive views on vaccine importance, effectiveness, and religious compatibility (t
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Melphalan is a clinical used alkylating antitumor agent
2018-11-14
Melphalan is a clinical-used alkylating antitumor agent and is often the drug of choice in the treatment of ovarian, melanoma, and breast cancer. Melphalan, shows a diversity of toxic side effects especially when used at a high dose (Casanova et al., 2012). Currently, we proved that ARS4, an artemis
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