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Numerous animal studies have demonstrated beyond
2019-06-18
Numerous animal studies have demonstrated beyond doubt that effective inhibition of osteoclastogenesis or osteoclast function significantly reduces metastatic tumour growth in bone [13–20]. Likewise, clinical trials in patients with non-metastatic or metastatic cancers established that treatment wit
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Several cases of injury to the circumflex artery owing
2019-06-18
Several cases of injury to the circumflex artery owing to ablation of the lateral mitral isthmus and inside the CS have been reported. The circumflex artery and the CS share a close relationship. Takahashi et al. reported the first case of acute circumflex artery occlusion during CS ablation, which
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Preamble The J wave syndromes JWSs consisting of the Brugada
2019-06-18
Preamble The J-wave syndromes (JWSs), consisting of the Brugada syndrome (BrS) and early repolarization syndrome (ERS), have captured the interest of the cardiology apoptosis inducer over the past 2 decades following the identification of BrS as a new clinical entity by Pedro and Josep Brugada in
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Sin considerar la poes a de
2019-06-18
Sin considerar la poesía de Villaurrutia en esta ocasión, es evidente que el pasaje citado representa una elocuente cristalización del su relevancia para el pensamiento y la poética de Octavio Paz. Es notable que el juicio crítico de Paz incluya referencias al universo —donde los opuestos coexisten
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br Methods br Results Characteristics of studies included in
2019-06-18
Methods Results Characteristics of studies included in the analysis are described in the accompanying Lancet paper. We included 119 studies (58 from high-income countries and 61 from low-income and middle-income countries) in this Beta-Lapachone cost analysis. Worldwide in 2010, an estimated
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As Canadians queue to vote in
2019-06-18
As Canadians queue to vote in the federal election next week, some will be uncomfortable knowing that the new Fair Elections Act that requires an official photo identification will overwhelmingly discriminate against those who are least likely to produce it—the very groups cited by UNCOHR. Many Cana
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br Introduction Worldwide trauma is currently the sixth
2019-06-18
Introduction Worldwide, trauma is currently the sixth leading cause of death, accounting for 10% of mortalities. The urogenital system has consistently been shown to be involved in 10% of patients presenting after trauma and is a significant factor in trauma-induced morbidity and mortality. Renal
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br Conflict of interest br Introduction br Case
2019-06-17
Conflict of interest Introduction Case report Discussion Dextrocardia is commonly associated with situs inversus totalis (incidence: 2 in 10,000 individuals) and rarely associated with situs solitus (incidence: 1 in 20,000 individuals). While associated cardiac anomalies are seen in appr
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br Materials and methods br Results br
2019-06-17
Materials and methods Results Discussion Conclusions Conflict of interest Acknowledgments Introduction Circumferential order BAY 41-2272 (PV) isolation has been accepted by a consensus as the strategy for the treatment of atrial fibrillation (AF) using catheter ablation [1–4].
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The excellent birth cohort study reported in by
2019-06-17
The excellent birth cohort study reported in by Heather Zar and colleagues, done in a periurban area outside Cape Town in South Africa, is a good example of a study that has provided important information about child pneumonia at a time of change. It provides the first incidence estimates of pneumo
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Villoro cuestiona la forma incorrecta en que es presentada l
2019-06-17
Villoro cuestiona la forma incorrecta en que es presentada la relación entre estos derechos como dos sujetos confrontados, en tanto que opina que no existe un sujeto colectivo en el mismo sentido que lo es el sujeto individual, sólo éste es intencional, el colectivo no es un ente que exista sin la p
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Parte de las idas y vueltas ten an
2019-06-17
Parte de las idas y vueltas tenían que ver con la negociación de un convenio sobre cooperación científico-técnica (suscrito el 27 de agosto de 1980), de uno financiero por un préstamo de 30 millones de dólares (firmado entre el 19 y el 24 de noviembre de 1980 entre el Banco Central argentino y el Ba
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Upon diagnosis the patient s lymphoma
2019-06-17
Upon diagnosis, the patient׳s lymphoma and HLH represented a therapeutic dilemma. Effective early therapy reduces mortality of HLH from 95% to 30–35% [4]. The HLH-2004 treatment protocol consists of T-cell targeted immunosupression with dexamethasone and cyclosporine, macrophage targeted etoposide w
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Countdown to concluded its tasks after the
2019-06-17
Countdown to 2015 concluded its tasks after the launch of its seventh global report at the Maternal Newborn Health conference in Mexico City, October, 2015. It is now relaunched as Countdown to 2030 (CD2030), retaining and enhancing the successful multi-institutional network with over a decade of he
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br Genetic basis for atrial standstill br Genetic
2019-06-15
Genetic basis for atrial standstill Genetic basis of conduction block Genes involved in cardiac development and bradycardia Development of the CCS is a complex biological process with the potential to be wrought with problems. Several transcription factors, including homeodomain proteins an
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