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Coagulopathy has been identified as a critical contributing
2018-11-02
Coagulopathy has been identified as a critical contributing factor in the development and recurrence of chronic SDH, acute SDH, and ICH. Sixty percent of patients with chronic SDH without a history of trauma were on antiplatelet medication. According to a retrospective study, anticoagulants increase
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It is well known that
2018-11-02
It is well known that in the studies on protein structure–activity relationships, the most basic requirement is to firstly obtain the bioactive protein with high purity and then to conduct research with different means and in different aspects. One relatively important way is to directly cleave (sep
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With the future rise in diabetic
2018-11-02
With the future rise in diabetic population worldwide, the search foractive compounds with α-glucosidase inhibitory activity from medicinal plants has become a very meaningful task. Furthermore, these compounds can be evaluated for potential pharmacological activity against other metabolic diseases.
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CD BMSCs formed heterotopic bone in vivo which corroborate
2018-11-02
CD34+ BMSCs formed heterotopic bone in vivo which corroborate their enrichment in osteoprogenitors. While in the present study, we employed CD34 as a marker that defines a specific lineage within BMSCs, it is plausible that CD34 plays a role in osteoblast differentiation. CD34 plays an important rol
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Importantly this recent paper Gonzalez Cordero et
2018-11-02
Importantly, this recent paper (Gonzalez-Cordero et al., 2013) together with our work confirms the capacity of pluripotent stem cells to provide a renewable source of cells to produce photoreceptors in vitro and highlights the great interest of using the 3D culture system developed by Sasai’s group.
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br Experimental Procedures br Author Contributions br
2018-11-02
Experimental Procedures Author Contributions Acknowledgments We thank Keisuke Okita and Shinya Yamanaka for providing the hiPSC lines 409B2 and 604B1, Knut Woltjen for providing PB-MCSII, Akitsu Hotta for providing the PBase II vector and instructions for transducing the piggyBac vectors, a
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Conversely not much is known about the origin
2018-11-02
Conversely, not much is known about the origin of these mutations. Their high frequency, combined with the proficient DNA repair of hESC (Sokolov and Neumann, 2013), suggests that these selective undergo profuse DNA damage in culture. Studies on genetic mosaicism in hESC cultures, which reflect the
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hepititis b Accumulating evidence indicates that treatment u
2018-11-02
Accumulating evidence indicates that treatment using extracellular vesicles (EVs) have multiple advantages over cell therapy, because EVs are stable in the circulation without losing function and exhibit a superior safety profile (Vader et al., 2016). In particular, MSCs are an attractive source of
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Scale similarity criteria the Rayleigh number and the
2018-11-02
Scale similarity criteria (the Rayleigh number and the rotation parameter, constructed from the scale quantities) specified in the course of the simulations, were determined for the conjugate and the non-conjugate settings as follows: where ΔT0 is the temperature difference (ΔT0=–). In the conjuga
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Narcolepsy may be mono symptomatic
2018-11-02
Narcolepsy may be mono-symptomatic (only ES) or oligo-symptomatic (ES and cataplexy). The degree of ES is variable and the attacks of cataplexy might involve several muscle groups being triggered by emotions [1,3]. The use of modafinil in the treatment of narcolepsy is a first option for the treatm
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Para Keynes que construye su m todo como un sistema
2018-11-01
Para Keynes, que construye su método como un sistema económico de tres variables independientes (la propensión marginal CGP-41251 consumir, la eficacia marginal del capital y la tasa de interés) que determinan a dos dependientes (el nivel de ingreso y el volumen de ocupación), la verdadera determina
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In order to further assess the
2018-11-01
In order to further assess the specificity of the 4-biomarker panel in detecting lung cancer patients, we collected a group of patients with benign lung diseases, including granuloma, pulmonary inflammatory pseudotumor, tuberculosis, pulmonary nodule and sequestration. Of note, these patients were d
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Thirty seven studies reported ReA following Campylobacter n
2018-11-01
Thirty-seven studies reported ReA following Campylobacter (n=19) and NTS infections (n=26) (Buxton et al., 2002, Bremell et al., 1991, Dworkin et al., 2001, Eastmond, 1983, Ekman et al., 2000, Gumpel et al., 1981, Hakansson et al., 1976, Hannu et al., 2002a, 2002b, Helms et al., 2006, Pitkanen et al
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Tumor relapse after radiotherapy is a
2018-11-01
Tumor relapse after radiotherapy is a significant challenge to oncologists. Tumor recurrence was generally due to radiation resistance, which was determined by both the intrinsic characteristics and the extrinsic microenvironment of cancer vorapaxar (Frank et al., 2010). The unique stem cell proper
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Findings from the most recent Global Burden
2018-11-01
Findings from the most recent Global Burden of Disease study, published in October 2016 in , show that in 2015, the mean life expectancy worldwide had reached roughly 72years. This is an increase of 10years since 2000, largely attributed to improvements in childbirth-associated and infant mortality,
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