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The importance of the finding
2018-11-06
The importance of the finding that the prostaglandin pathway is selectively downregulated by MSX2, but not MSX1, is 2-fold; i) this functional disparity between MSX1 and MSX2 provides a mechanistic insight into a cellularization event during muscle dedifferentiation and ii) it also demonstrates that
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Molecular karyotyping identified a novel
2018-11-06
Molecular karyotyping identified a novel 2.4Mb gain on chromosome 5p14.3 and a gain on chromosome 12p11.21, which was also found in KCL040. The gain on chromosome 5p14.3 containing a single gene, CDH18 (Cadherin-18), was also present in one of two sibling cell lines, KCL032, but not in KCL034, a th
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In the present study we have used
2018-11-06
In the present study, we have used a set of OSCC cell lines and isolated the putative stem cell fraction (CD44highCD24low) along with CD44highCD24high and CD44lowCD24high (non-stem) sub-populations. These populations were subjected to various molecular and cellular assays to determine whether CD24 h
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cathepsin inhibitor In summary our findings indicated that m
2018-11-05
In summary, our findings indicated that miR-375 promoted the osteogenic differentiation of hASCs both in vitro and in vivo, and miR-375 targeted DEPTOR to inhibit the activity of AKT signaling during this process. Furthermore, YAP1 together with miR-375 established a negative feedback loop to regul
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Since the p p axis has
2018-11-05
Since the p53/p21 axis has been described as an impairment mechanism of FA-deficient HSCs and also plays important roles in other models of HSC aging (Choudhury et al., 2007), we evaluated the effect of PPARγ on CDKN1a expression. We found that inhibition of PPARγ downregulated the expression of CDK
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Western blot analysis The proteins contained in hippocampal
2018-11-05
Western blot analysis. The proteins contained in hippocampal lysates were separated electrophoretically in polyacrylamide gel consisting of 0.375 M Tris–HCl (pH 8.8), 0.1% SDS, 0.1% TEMED, 10% acrylamide, 0.3% bisacrylamide. Stereotactic injections of viruses into the CA1 region of the mouse hippoc
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Magnetohydrodynamic MHD flow and heat transfer for
2018-11-05
Magnetohydrodynamic (MHD) flow and heat transfer for a fluid has enormous applications in many engineering problems such as MHD power generators, petroleum industries, plasma studies, geothermal nop receptor extractions, the boundary layer control in the field of aerodynamics and many other applica
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Aside from the obvious physical damage the attacks incurred
2018-11-05
Aside from the obvious physical damage the attacks incurred, acts of terrorism have been shown to have an immediate and longer-term negative effect on mao inhibitors list mental health (Silver, Holman, McIntosh, Poulin & Gil-Rivas, 2002; Whalley & Brewin, 2007). This may be the result of two mechan
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br Previous research on informal care provision and
2018-11-05
Previous research on informal care provision and health Previous studies exploring the link between provision of informal care and health reflect the complexity of researching this topic area. Cross-sectional analyses may be limited in examining the factors preceding or following an individual\'s
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br Discussion Research from diverse global contexts confirms
2018-11-05
Discussion Research from diverse global contexts confirms that children born premaritally experience distinct health and developmental challenges compared to children born to married mothers (Singh, 1998). In sub-Saharan Africa, the consequences of being born premaritally are especially severe, i
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The broad societal changes that are driving
2018-11-05
The broad societal changes that are driving African women to marry at older ages, and thus experience prolonged risk of having a premarital birth, could, however, condition the experience of having a premarital birth in a way that lessens its consequences for children (Garenne & Zwang, 2006a). One s
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To illustrate consider how a young black man may experience
2018-11-05
To illustrate, consider how a young black man may experience his blackness when he is home with family and friends compared to if he is pulled over by the police for a minor traffic infraction. In this example, there may be neutral or positive psychosocial import of being black when with family and
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In addition stigma experienced by the study participants can
2018-11-05
In addition, stigma experienced by the study participants can explain the low rate and inverse effect of glutathione reductase participation. Stigma against PLWH is a known barrier to accessing HIV testing and care. Perceived stigma negatively affects the quality of life (QoL) of PLWH (Holzemer et
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dihydrochloride First an understanding of policymaker charac
2018-11-05
First, an understanding of policymaker characteristics associated with public health policy voting can contribute to a small, but growing body of knowledge about how advocates (e.g., citizens, community leaders, researchers, professional societies) might cultivate support for science-based public he
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The stability In the actual experiments the
2018-11-05
In the actual experiments, the gas flow rates were operated in the range of 8.297 × 10−4 m3/s to 27.65 × 10−4 m3/s and the liquid flow rates were in the range 20.649 × 10−6 m3/s to 48.183 × 10−6 m3/s. As the experiment proceeds, the liquid started forming a layer which is clear liquid (ScL) and its
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