• Bisphosphonates are a well established

  2019-06-10

  

  Bisphosphonates are a well-established, standard-of care treatment option to reduce the frequency and severity and time of onset of the skeletal related events (SREs) in patients with bone metastases due to either solid tumours or multiple myeloma [21–33]. From many years, BPs have been incorporated

• In this study we applied

  2019-06-10

  

  In this study, we applied a more general approach along these lines, which has previously been used only in few reports in the literature [8]. Based on a prospective BC database including all newly diagnosed BC cases at a large Swiss breast center over a 20-year period, we aimed to give a comprehens

• Nademanee et al reported nine

  2019-06-10

  

  Nademanee et al. reported nine symptomatic patients with BrS who experienced VF and underwent electrophysiological study and catheter ablation [8]. The patients exhibited abnormal epicardial electrograms characterized by fragmented electrograms with a relatively low voltage ( Idiopathic ventricular

• Poco despu s el de julio y reimpreso en

  2019-06-10

  

  Poco después, el 19 de julio (y reimpreso en al menos siete números siguientes), se publica en la última página del mismo diario un anuncio donde de nuevo figura la América poética, esta vez entre las novedades de la mencionada librería. La acompañan ahora La guerra de las mujeres (1845) de Alejandr

• Introduction Atrial fibrillation AF is a

  2019-06-10

  

  Introduction Atrial fibrillation (AF) is a common cardiac arrhythmia that becomes more prevalent with age [1] and is associated with an increased long-term risk of stroke, MDV3100 failure, and all-cause mortality [2]. Since Einthoven recorded the electrograms in 1906 [3], AF has widely been recogni

• Aggressive osteoblastoma is characterized by epithelioid ost

  2019-06-10

  

  Aggressive osteoblastoma is characterized by epithelioid osteoblasts that are, two to three times larger than conventional osteoblasts, and have abundant eosinophilic cytoplasm, large vesicular eccentric round to oval nuclei with prominent nucleoli. Usually there are rare or absence of mitoses and i

• Acute kidney injury is a common disorder

  2019-06-06

  

  Acute kidney injury is a common disorder worldwide, occurring in more than 13 million people every year, 85% of whom live in low-income or middle-income countries (LMICs). The disease imposes a severe burden of morbidity and mortality, with a major economic effect on health-care expenditure worldwid

• Two important issues affect our interpretation

  2019-06-06

  

  Two important issues affect our interpretation of these findings. First, many women chose institutional delivery (53% of deliveries were at hospitals in Sazawal and colleagues\' trial, and 64% in Semrau and colleagues\' trial). The latest WHO guidelines recommend application of chlorhexidine to the

• Second political regime does very

  2019-06-06

  

  Second, political regime does very little to explain differences between countries. Rwanda, Congo (Brazzaville), and Tanzania have very similar child mortality rates (between 40 and 60 deaths per 1000 livebirths in 2014) to South Africa, Botswana, and Namibia despite the former countries being consi

• order Torin1 Apart from their association with severe pain a

  2019-06-06

  

  Apart from their association with severe pain and reduced quality of life, SREs require substantial healthcare resource utilization (HRU) in their treatment and management. Previous retrospective studies have attempted to quantify various aspects of the burden of SREs across specific tumor types/cou

• KU-60019 cost br Conflict of interest br Acknowledgments The

  2019-06-06

  

  Conflict of interest Acknowledgments The project has been supported by grants from Science Foundation Ireland, Ireland (Starting Investigator Research Grant to ES, 09/SIRG/B1575, TIDA to ES 12/TIDA/B2388) and by the Millennium Fund of NUIG. The t(3;21)(q26;q22) is a rare cytogenetic abnorma

• withaferin a Although the NCCN IPI is a promising simple sca

  2019-06-06

  

  Although the NCCN-IPI is a promising simple scale based on conventional clinical factors, its usefulness remains controversial [6,7]. It should be evaluated in populations of different regions and ethnicities before adopting it for routine clinical use. Conflict of interest Report At presenta

• Clinical symptoms consist of the pacemaker syndrome includin

  2019-06-06

  

  Clinical symptoms consist of the pacemaker syndrome, including palpitations and hemodynamic instability, as in our case. The definitive management of RNRVAS requires sufficient time for the atrial tissue to recover from the refractory period. Barold et al. reviewed several general modes that could p

• br Other candidate genes br The frequency of minor gene

  2019-06-06

  

  Other candidate genes The frequency of minor gene mutations in BrS As mentioned above, more than 10 genes have been reported to cause BrS. The proportions of BrS patients who are mutation carriers, however, are very small, except in the case of SCN5A. In a recent extensive mutation analysis of

• In patients with ovary lesions surgical intervention play an

  2019-06-06

  

  In patients with ovary lesions, surgical intervention play an important role to establish correct diagnosis. First of all, obtaining histologic confirmation of disease by laparotomy is critical in differentiating primary ovarian cancer between metastatic lesions such as gastric cancer to the ovary (

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