• The ETV ABL fusion has been

  2019-06-28

  

  The ETV6-ABL1 fusion has been reported as a poor prognostic factor when found in acute leukemia (AML and ALL) and MDS. The prognostic significance of an ETV6/ABL1 chronic myeloproliferative neoplasm is less clear due to the paucity of cases and the lack of controlled clinical trials [5]. There is a

• Both stunting and environmental enteric dysfunction improve

  2019-06-28

  

  Both stunting and environmental enteric dysfunction improve with radical shifts in environment, such as Efavirenz or local economic development. This improvement is reflected to some extent by the smoothing of the seasonality of undernutrition reported by Nabwera and colleagues in these three Gambi

• br More than any other

  2019-06-28

  

  More than any other disease group, injuries chart the story of a country\'s development in real time. China has seen major changes in injury causes and risks over the past three decades attributable to rapid urbanisation, motorisation, and occupational shifts, as well as health reforms and demogra

• br How do you manage patients

  2019-06-28

  

  How do you manage patients on intravenous bone-targeted agents who require dental work? For patients who are on IV bisphosphonate therapy and require dento-alveolar procedures there is a suggestion that prophylactic antibiotic use around the procedure may be helpful in reducing ONJ risk [45,49].

• More recently primary tumor driven generation of a bone pre

  2019-06-28

  

  More recently, primary tumor driven generation of a bone pre-metastatic niche was observed in a mouse model of estrogen receptor-negative breast cancer metastasis. Specifically, lysyl oxidase (LOX) secreted into the circulation from hypoxic primary breast tumors disrupted bone homeostasis, thereby i

• br Discussion Bone marrow fibrosis

  2019-06-28

  

  Discussion Bone marrow fibrosis is known to be associated with hematolymphoid malignancies such as acute leukemia, Hodgkin and non-Hodgkin lymphoma. Among the acute leukemias, marrow fibrosis is most often seen with acute megakaryoblastic leukemia. It is an uncommon finding in APL and till date o

• Of note gender equity might continue despite

  2019-06-28

  

  Of note, gender equity might continue despite the economic development of a society. Studies by Nussbaum and Sen have shown no direct relation between wealth and equity. Hence, some countries with high wealth, such as Saudi Arabia, also a have high degree of gender inequity, whereas others with low

• HRU resulting from SREs is of

  2019-06-28

  

  HRU resulting from SREs is of increasing relevance in times of financial and economic restraint because it can help to determine the financial burden to hospital managers and payers. A separate analysis of the costs associated with SREs in this study found that the most costly SRE, spinal cord compr

• br Grant support This work was supported by INSERM

  2019-06-28

  

  Grant support This work was supported by INSERM, the “Ligue Contre le Cancer” (Equipe Labellisée LIGUE 2012; grant EL2012NCC/DH), the “Fédération Nationale Enfants et Santé” and the “Société Française de lutte contre les Cancers et les leucémies de l\'Enfant et de l\'Adolescent(“appel à projet 20

• br Materials and methods br Results We observed

  2019-06-28

  

  Materials and methods Results We observed 3 patterns of response to PHP. Pattern 1, observed in 56% of patients (nos. 4, 6, 7, 8, and 9), was characterized by S–A and V–A intervals in the septal region that were identical whether HB was captured or not, along with an unchanged atrial activatio

• Resulta dif cil un censo de poetas

  2019-06-28

  

  Resulta difícil un censo de poetas (aunque la Coordinación Nacional de Literatura del inba o de Conaculta probablemente cuente con las herramientas para hacerlo) y volver Sulconazole Nitrate trillar sobre un concepto ingenioso como el de asamblea de poetas pergeñado por Zaid en 1980 parece imposible

• Introduction Atrial fibrillation AF is

  2019-06-27

  

  Introduction Atrial fibrillation (AF) is the most common arrhythmia in adults and the most common cause of embolic stroke. AF affects approximately 0.8 million patients in Japan alone, and its incidence is expected to grow exponentially [1–3]. However, the electrophysiological mechanisms of the ini

• notch signaling Introduction Personalized medicine is the ma

  2019-06-27

  

  Introduction Personalized medicine is the major goal of translational research in the post-genomic era. Numerous biomarkers have been identified by genomic or proteomic approach that can reclassify the disease notch signaling and predict clinical outcome. However, to define a specific disease pheno

• In this section we will try and address many of

  2019-06-27

  

  In this section we will try and address many of the frequently asked questions around preventive and prophylactic measures for patients either starting or already established on bone-targeted therapy (Figs. 2 and 3). In view of the difficulties in treating ONJ, preventive strategies would seem to ma

• br En general los resultados electorales

  2019-06-27

  

  En general, los resultados electorales de 2011 demuestran la identificación y cercanía lograda entre los movimientos sociales y Ollanta Humala, por lo menos en términos de adhesión electoral, la misma que se mantuvo en el tiempo pues en 2006 también estos sectores le otorgaron su voto. Así, la ele

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