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Prior case reports have described hematological remission
2019-06-29
Prior case reports have described hematological remission in patients with myelofibrosis during treatment with bisphosphonates, but a phase II study investigating the effects of zoledronic calcium sensing receptor on patients with myelofibrosis showed responses in only 1 of 16 patients[13]. In conc
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Although the NCCN IPI is a promising
2019-06-29
Although the NCCN-IPI is a promising simple scale based on conventional clinical factors, its usefulness remains controversial [6,7]. It should be evaluated in populations of different regions and ethnicities before adopting it for routine clinical use. Conflict of interest Report At presenta
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Several true lumen re entry
2019-06-29
Several true lumen re-entry devices have been introduced into the market, including the Outback catheter, allowing fluoroscopically controlled true arterial lumen re-entry after subintimal guidewire passage. A recent retrospective review reported a successful re-entry rate of 91% in 11 patients wit
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Podemos seguir con ejemplos espigados
2019-06-28
Podemos seguir con ejemplos espigados: el plan de instrucción pública del peruano Hipólito Unanue, tras la obligada crítica al antiguo régimen, preveía estudios de “humanidades y filosofía en lengua vulgar entrando después en el estudio del latín los que lo hubieran menester”. En Venezuela se quiso
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The ETV ABL fusion has been
2019-06-28
The ETV6-ABL1 fusion has been reported as a poor prognostic factor when found in acute leukemia (AML and ALL) and MDS. The prognostic significance of an ETV6/ABL1 chronic myeloproliferative neoplasm is less clear due to the paucity of cases and the lack of controlled clinical trials [5]. There is a
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Both stunting and environmental enteric dysfunction improve
2019-06-28
Both stunting and environmental enteric dysfunction improve with radical shifts in environment, such as Efavirenz or local economic development. This improvement is reflected to some extent by the smoothing of the seasonality of undernutrition reported by Nabwera and colleagues in these three Gambi
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br More than any other
2019-06-28
More than any other disease group, injuries chart the story of a country\'s development in real time. China has seen major changes in injury causes and risks over the past three decades attributable to rapid urbanisation, motorisation, and occupational shifts, as well as health reforms and demogra
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br How do you manage patients
2019-06-28
How do you manage patients on intravenous bone-targeted agents who require dental work? For patients who are on IV bisphosphonate therapy and require dento-alveolar procedures there is a suggestion that prophylactic antibiotic use around the procedure may be helpful in reducing ONJ risk [45,49].
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More recently primary tumor driven generation of a bone pre
2019-06-28
More recently, primary tumor driven generation of a bone pre-metastatic niche was observed in a mouse model of estrogen receptor-negative breast cancer metastasis. Specifically, lysyl oxidase (LOX) secreted into the circulation from hypoxic primary breast tumors disrupted bone homeostasis, thereby i
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br Discussion Bone marrow fibrosis
2019-06-28
Discussion Bone marrow fibrosis is known to be associated with hematolymphoid malignancies such as acute leukemia, Hodgkin and non-Hodgkin lymphoma. Among the acute leukemias, marrow fibrosis is most often seen with acute megakaryoblastic leukemia. It is an uncommon finding in APL and till date o
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Of note gender equity might continue despite
2019-06-28
Of note, gender equity might continue despite the economic development of a society. Studies by Nussbaum and Sen have shown no direct relation between wealth and equity. Hence, some countries with high wealth, such as Saudi Arabia, also a have high degree of gender inequity, whereas others with low
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HRU resulting from SREs is of
2019-06-28
HRU resulting from SREs is of increasing relevance in times of financial and economic restraint because it can help to determine the financial burden to hospital managers and payers. A separate analysis of the costs associated with SREs in this study found that the most costly SRE, spinal cord compr
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br Grant support This work was supported by INSERM
2019-06-28
Grant support This work was supported by INSERM, the “Ligue Contre le Cancer” (Equipe Labellisée LIGUE 2012; grant EL2012NCC/DH), the “Fédération Nationale Enfants et Santé” and the “Société Française de lutte contre les Cancers et les leucémies de l\'Enfant et de l\'Adolescent(“appel à projet 20
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br Materials and methods br Results We observed
2019-06-28
Materials and methods Results We observed 3 patterns of response to PHP. Pattern 1, observed in 56% of patients (nos. 4, 6, 7, 8, and 9), was characterized by S–A and V–A intervals in the septal region that were identical whether HB was captured or not, along with an unchanged atrial activatio
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Resulta dif cil un censo de poetas
2019-06-28
Resulta difícil un censo de poetas (aunque la Coordinación Nacional de Literatura del inba o de Conaculta probablemente cuente con las herramientas para hacerlo) y volver Sulconazole Nitrate trillar sobre un concepto ingenioso como el de asamblea de poetas pergeñado por Zaid en 1980 parece imposible
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